Kerem Teralı


Tıp Fakültesi

Telefon numarası +90 392 671 11 11
Dahili 2561
Ofis MD201
Diğer bilgiler

B.M. Sürdürülebilir Kalkınma Amaçları

Sağlık ve Kaliteli Yaşam

Öz geçmiş

Öğrenim Durumu
  • Queen Mary, University of London (QMUL) Biochemistry (Doktora, 2010)
  • University of St. Andrews Structural Proteomics (Yüksek Lisans, 2006)
  • Istanbul Technical University (ITU) Molecular Biology and Genetics (Lisans, 2005)

Uluslararası hakemli dergilerde yayınlanan makaleler (SCI,SSCI,Arts and Humanities)

  • • Yildiz, A.K., Bulbul, A., Bekmez, B.O., Turkyilmaz, A., Terali, K., Cakir, A.D. & Ucar, A. (2023). A rare presentation of homozygous pathogenic variant in MC2R gene with salt-wasting crisis in a neonate. Molecular Syndromology, doi: 10.1159/000533986 - 2023
  • • Teralı, K., Türkyılmaz, A., Sağer, S.G. & Çebi, A.H. (2023). Prediction of molecular phenotypes for novel SCN1A variants from a Turkish genetic epilepsy syndromes cohort and report of two new patients with recessive Dravet syndrome. Clinical and Translational Science, doi: 10.1111/cts.13679 - 2023
  • Şen, A., Özbeyli, D., Teralı, K., Göger, F., Yıldırım, A., Ertaş, B., Doğan, A., Bitiş, L. & Şener, G. (2023). Protective effects of Rubus tereticaulis leaves ethanol extract on rats with ulcerative colitis and bio-guided isolation of its active compounds: A combined in silico, in vitro and in vivo study. Chemico-Biological Interactions, vol. 369, p. 110263. - 2023
  • Markus, V., Paul, A.A., Teralı, K., Özer, N., Marks, R.S., Golberg, K. & Kushmaro, A. (2023). Conversations in the Gut: The Role of Quorum Sensing in Normobiosis. International Journal of Molecular Sciences, vol. 24, no. 4, p. 3722. - 2023
  • Zaid, M.A., Dalmizrak, O., Teralı, K. & Ozer, N. (2023). Mechanistic insights into the inhibition of human placental glutathione S-transferase P1-1 by abscisic and gibberellic acids: an integrated experimental and computational study. Journal of Molecular Recognition, vol. 36, no. 9, p. e3050. - 2023
  • Güran, M., Çakıral, K., Teralı, K., Kandemir, T., Şanlıtürk, G., Öcal, M.M., Nagiyev, T. & Köksal, F. Meropenem in combination with baicalein exhibits synergism against extensively- and pan-drug-resistant A. baumannii clinical isolates in vitro. Pathogens and Disease, vol. 81, pp. 1–11. - 2023
  • Gençosman, S., Ceylanlı, D., Şehirli, A.Ö., Teralı, K., Bölükbaşı, F., Çetinel, Ş. & Sayıner, S. (2022). Investigation of the possible protective effect of N-acetylcysteine (NAC) against irinotecan (CPT-11)-induced toxicity in rats. Antioxidants, vol. 11, no. 11, p. 2219. - 2022
  • Ceylanlı, D., Şehirli, A.Ö., Gençosman, S., Teralı, K., Şah, H., Gülmez, N. & Sayıner, S. (2022). Protective effects of alpha-lipoic acid against 5-fluorouracil-induced gastrointestinal mucositis in rats. Antioxidants, vol. 11, no. 6, p. 1930. - 2022
  • Diker, S., Gelener, P., Teralı, K., Ergoren, M.C., Tunca, C, Başak, A.N. & Tan, E. (2022). A combined clinical and computational approach to understand the SOD1A4T-mediated pathogenesis of rapidly progressive familial amyotrophic lateral sclerosis. Acta Neurologica Belgica, vol. 122, pp. 955–960. - 2022
  • Ghali, U.M., Teralı, K., Dalmızrak, Ö. & Özer, N. (2022). Rethinking common solvents in butyrylcholinesterase activity assays. Inorganic Chemistry Communications, vol. 143, p. 109796. - 2022
  • Ak Sakallı, E., Teralı, K., Karadağ, A.E., Biltekin, S.N., Kosar, M., Demirci, B., Baser, K.H.C. & Demirci, F. (2022). In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of Eucalyptus essential oils, 1,8-cineole and citronellal. Natural Product Communications, vol. 17, no. 6, pp. 1–8. - 2022
  • Dogan, M., Eroz, R., Bolu, S., Yüce, H., Gezdirici, A., Arslanoğlu, İ. & Teralı, K. (2022). Study of ten causal genes in Turkish patients with clinically suspected maturity-onset diabetes of the young (MODY) using a targeted next-generation sequencing panel. Molecular Biology Reports, vol. 49, no. 8, pp. 7483–7495. - 2022
  • Markus, V., Dalmızrak, Ö., Teralı, K. & Özer, N. (2022). The inhibition of glutathione S-transferases and butyrylcholinesterase by antidepressants: a mini-review on enzyme–drug interactions. Current Enzyme Inhibition, vol. 18, no. 2, pp. 82–91. - 2022
  • Demirci, F., Terali, K., Karadağ, A.E., Biltekin, S.N., Ak Sakallı, E., Koşar, M., Demirci, B. & Baser, K.H.C. (2022). In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of Origanum essential oils and carvacrol. Planta Medica, DOI: 10.1055/a-1828-2479 - 2022
  • Aykac, A., Teralı, K., Özbeyli, D., Ede, S., Albayrak, Ö., Başer, K.H.C. & Şener, G. (2022). A multi-parameter evaluation of the neuroprotective and cognitive-enhancing effects of Origanum onites L. (Turkish oregano) essential oil on scopolamine-induced amnestic rats. Metabolic Brain Disease, vol. 37, no. 4, pp. 1041–1055. - 2022
  • Golberg, K., Markus, V., Kagan, B.-e., Barzanizan, S., Yaniv, K.; Teralı, K., Kramarsky-Winter, E., Marks, R.S. & Kushmaro, A. (2022). Anti-virulence activity of 3,3′-diindolylmethane (DIM): a bioactive cruciferous phytochemical with accelerated wound healing benefits. Pharmaceutics, vol. 14, no. 5, p. 967. - 2022
  • Ünlü, A., Teralı, K., Aydın, Z.U., Dönmez, A.A., Yusufoğlu, H.S. & Çalış, İ. (2022). Isolation, characterization and in silico studies of secondary metabolites from the whole plant of Polygala inexpectata Peşmen & Erik. Molecules, vol. 27, no. 3, p. 684. - 2022
  • Ozbeyli, D., Sen, A., Aykac, A., Terali, K., Cilingir-Kaya, O.T., Senkardes, I. & Sener, G. (2021). Therapeutic effects of Momordica charantia L. ethanolic extract on acetic acid-induced ulcerative colitis in rats. European Journal of Biology, vol. 80, no. 2, pp. 119–128. - 2021
  • Markus, V., Share, O., Shagan, M., Halpern, B., Bar, T., Kramarsky-Winter, E., Teralı, K., Özer, N., Marks, R.S., Kushmaro, A. & Golberg, K. (2021). Inhibitory effects of artificial sweeteners on bacterial quorum sensing. International Journal of Molecular Sciences, vol. 22, no. 18, p. 9863. - 2021
  • Shukur, K., Fallah, A., Teralı, K., Kalkan, R., Gazi, M. & Gülcan, H.O. (2021). 3-Hydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one and 3-hydroxy-6H-benzo[c]chromen-6-one act as ON-OFF selective fluorescent sensors for iron(III) under in vitro and ex vivo conditions. Turkish Journal of Chemistry, vol. 45, no. 3, pp. 858–867. - 2021
  • Pasandideh, R., Gazi, M., Teralı, K. & Oladipo, A.A. (2021). Fabrication of human genomic DNA encapsulated supermacroporous alginate beads. Materials Technology, vol. 36, no. 6, pp. 331–338. - 2021
  • Markus, V., Golberg, K., Teralı, K., Ozer, N., Kramarsky-Winter, E., Marks, R.S. & Kushmaro, A. (2021). Assessing the molecular targets and mode of action of furanone C-30 on Pseudomonas aeruginosa quorum sensing. Molecules, vol. 26, no. 6, p. 1620. - 2021
  • Doğan, M., Eröz, R., Terali, K., Gezdirici, A. & Bolu, S. (2021). Clinical, radiological and computational studies on two novel GNPTG variants causing mucolipidosis III gamma phenotypes with varying severity. Molecular Biology Reports, vol. 48, pp. 1465–1474. - 2021
  • Gezdirici, A., Teralı, K., Gülec, E.Y., Bornaun, H., Dogan, M. & Eröz, R. (2021). An integrated clinical and molecular study of a cohort of Turkish patients with Marfan syndrome harboring known and novel FBN1 variants. Journal of Human Genetics, vol. 66, pp. 647–657. - 2021
  • Dogan, M., Teralı, K., Eroz, R., Demirci, H. & Kocabay, K. (2021). Clinical and molecular findings in a Turkish family with an ultra-rare condition, ELP2-related neurodevelopmental disorder. Molecular Biology Reports, vol. 48, pp. 701–708. - 2021
  • Markus, V., Share, O., Teralı, K., Ozer, N., Marks, R.S., Kushmaro, A. & Golberg, K. (2020). Anti-quorum sensing activity of stevia extract, stevioside, rebaudioside A and their aglycon steviol. Molecules, vol. 25, no. 22, p. 5480. - 2020
  • Teralı, K., Baddal, B. & Gülcan, H.O. (2020). Prioritizing potential ACE2 inhibitors in the COVID-19 pandemic: insights from a molecular mechanics-assisted structure-based virtual screening experiment. Journal of Molecular Graphics and Modelling, vol. 100, p. 107697. - 2020
  • Gelener, P., Severino, M., Diker, S., Teralı, K., Tuncel, G., Tuzlalı, H., Manara, E., Paolacci, S., Bertelli, M. & Ergoren, M.C. (2020). Adult-onset glutaric aciduria type I: rare presentation of a treatable disorder. Neurogenetics, vol. 21, no. 3, pp. 179–186. - 2020
  • Dalmizrak, O., Teralı, K., Asuquo, E.B., Ogus, I.H. & Ozer, N. (2019). The relevance of glutathione reductase inhibition by fluoxetine to human health and disease: insights derived from a combined kinetic and docking study. Protein Journal, vol. 38, no. 5, pp. 515‒524. - 2019
  • Alegbe, E.O., Teralı, K., Olofinsan, K.A., Surgun, S., Ogbaga, C. & Ajiboye, T.O. (2019). Antidiabetic activity-guided isolation of gallic and protocatechuic acids from Hibiscus sabdariffa calyxes. Journal of Food Biochemistry, vol. 43, no. 7, p. e12927. - 2019
  • Teralı, K. & Ergören, M.Ç. (2019). The contribution of NOS3 variants to coronary artery disease: a combined genetic epidemiology and computational biochemistry perspective. International Journal of Biological Macromolecules, vol. 123, pp. 494‒499. - 2019
  • Dalmizrak, O., Teralı, K., Yetkin, O., Ogus, I.H. & Ozer, N. (2019). Computational and experimental studies on the interaction between butyrylcholinesterase and fluoxetine: implications in health and disease. Xenobiotica, vol. 49, no. 7, pp. 803‒810. - 2019
  • Teralı, K., Dalmizrak, O., Uzairu, S.M. & Ozer, N. (2019). New insights into the interaction between mammalian butyrylcholinesterase and amitriptyline: a combined experimental and computational approach. Turkish Journal of Biochemistry, vol. 44, no. 1, pp. 55‒61. - 2019
  • Ergoren, M.C., Turkgenc, B, Teralı, K., Rodoplu, O., Verstraeten, A., Van Laer, L., Mocan, G., Loeys, B. Tetik, O. & Temel, S.G. (2019). Identification and characterization of a novel FBN1 gene variant in an extended family with variable clinical phenotype of Marfan syndrome. Connective Tissue Research, vol. 60, no. 2, pp. 146‒154. - 2019
  • Teralı, K., Dalmizrak, O., Hoti, Q. & Ozer, N. (2018). Evaluation of the inhibitory effect of abamectin on mammalian butyrylcholinesterase: enzyme kinetic and molecular docking studies. Journal of Environmental Science and Health, Part B, vol. 53, no. 11, pp. 713‒718. - 2018
  • Ergören, M.Ç. & Teralı, K. (2018). Assessment of the association between three perplexing PPARA gene polymorphisms and risk of coronary artery disease in a population of Turkish Cypriot women. Cyprus Journal of Medical Sciences, vol. 3, no. 2, pp. 75‒80. - 2018
  • Ibitoye, O.B., Olofinsan, K., Teralı, K., Ghali, U.M. & Ajiboye, T.O. (2018). Bioactivity‐guided isolation of antidiabetic principles from the methanolic leaf extract of Bryophyllum pinnatum. Journal of Food Biochemistry, vol. 42, no. 5, p. e12627. - 2018
  • Teralı, K. (2018). An evaluation of neonicotinoids’ potential to inhibit human cholinesterases: protein–ligand docking and interaction profiling studies. Journal of Molecular Graphics and Modelling, vol. 84, pp. 54‒63. - 2018
  • Markus, V., Teralı, K., Dalmizrak, O. & Ozer, N. (2018). Assessment of the inhibitory activity of the pyrethroid pesticide deltamethrin against human placental glutathione transferase P1-1: a combined kinetic and docking study. Environmental Toxicology and Pharmacology, vol. 61, pp. 18‒23. - 2018
  • Dalmizrak, O., Teralı, K., Abdullah, R.K. & Ozer, N. (2018). Mechanistic and structural insights into the in vitro inhibitory action of hypericin on glutathione reductase purified from baker's yeast. Journal of Biochemical and Molecular Toxicology, vol. 32, no. 5, p. e22051. - 2018
  • Gurkan, C., Sevay, H., Demirdov, D.K., Hossoz, S., Ceker, D., Teralı, K. & Erol, A.S. (2017). Turkish Cypriot paternal lineages bear an autochthonous character and closest resemblance to those from neighbouring Near Eastern populations. Annals of Human Biology, vol. 44, no. 2, pp. 164‒174. - 2017
  • Teralı, K. & Yilmazer, A. (2016). New surprises from an old favourite: the emergence of telomerase as a key player in the regulation of cancer stemness. Biochimie, vol. 121, pp. 170‒178. - 2016
  • Teralı, K., Zorlu, T., Bulbul, O. & Gurkan, C. (2014). Population genetics of 17 Y-STR markers in Turkish Cypriots from Cyprus. Forensic Science International: Genetics, vol. 10, pp. e1‒e3. - 2014
  • Teralı, K., Beavil, R.L., Pickersgill, R.W. & van der Giezen, M. (2013). The effect of the adaptor protein Isd11 on the quaternary structure of the eukaryotic cysteine desulphurase Nfs1. Biochemical and Biophysical Research Communications, vol. 440, no. 2, pp. 235‒240. - 2013
Çalışma Alanları
  • Moleküler Biyoloji
  • Biyokimyasal Genetik
  • Protein Biyokimyası
  • Moleküler Enzimoloji
  • Hesapsal Biyokimya
  • Biyokimyasal Toksikoloji
İdari Görevler
  • Tıp Fakültesi'nde Doçent Temsilcisi (2022-2023)
  • Tıp Programı Dönem 3 Koordinatör Yardımcısı (2022-2023)
  • Tıp Fakültesi Dekan Yardımcısı (2023-DEVAM EDİYOR)